Cinnamon-Mediated Green Synthesis of Silver Nanoparticles with Potent Antibacterial Activity Against Oral Staphylococcus aureus Isolates
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Abstract
Staphylococcus aureus (S. aureus) is an important opportunistic bacterial pathogen associated with a wide range of infections, especially oral mucosa. As a result of the increasing emergence of antimicrobial-resistant strains, silver nanoparticles (AgNPs) have attracted considerable attention as an antibacterial approach. Cinnamomum has been shown to exhibit antibacterial and l properties and does not induce antimicrobial resistance. Fifty samples of oral mucosa (mucosa, tongue, and cheek) were collected from patients admitted to the Second Specialized Dental Health Center in Baquba City with a sterile cotton gel swab. 25 samples were taken from suspected cases of gingivitis, and 25 samples from apparently healthy individuals during the period of the study from April- June 2026. The results showed that the synthesized silver nanoparticles exhibited concentration-dependent antibacterial activity against Staphylococcus aureus. In conclusion, synthesized AgNPs are a promising antibacterial agent against Staphylococcus aureus, warranting further research to confirm their safety and practical applicability.
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