Vital Pulp Capping: Historical Review and Update Vital Pulp Capping & Historical Review
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Abstract
Abstract
The vital pulp capping aims to keep the exposed pulp alive by treating it. Secondary dentin, peritubular dentin (sclerosis), and reparative dentin are all products of living pulp tissue, which responds to biological and pathologic factors during a tooth's lifetime. Vital Pulp Capping revealed numerous research and published articles. Subsequently, this historical review intended to focus on the historical application of different materials used for preserving the vitality of the tooth pulp and indirect pulp capping, including Calcium phosphate, Calcium hydroxide, Zinc oxide eugenol cement, Corticosteroids and antibiotics, and others in published articles. A comprehensive electronic search was done using selected terms including Pulp capping agent, Stimulate reparative dentin formation, Maintain pulpal vitality, Release fluoride to prevent secondary caries, and Bactericidal or bacteriostatic, Adhere to dentin in different databases (PubMed et al.) for relevant published literature. The results showed various published articles over centuries on the development of different materials used to preserve the vitality of the tooth pulp. In conclusion, this review article revealed numerous published articles that displayed the development and application of materials used for tooth pulp capping. The author recommends addressing the limitation factors faced during this study to improve the reliability and contribution of Vital Pulp Capping in clinical applications.
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References
1. Stockton LW. Vital Pulp Capping: A Worthwhile Procedure. J Can Dent Assoc. 1999; 65:328-31
2. Cohen BD, Combe EC. Development of new adhesive pulp capping materials. Dent Update. 1994;21(2):57–62.
3. Qureshi A, E S, Nandakumar, Pratapkumar, Sambashivarao. Recent advances in pulp capping materials: an overview. J Clin Diagn Res. 2014 Jan;8(1):316-21. doi: 10.7860/JCDR/2014/7719.3980.
4. Huang H, Luo L, Li L, Guan Y, Yan Y, Jiang Z, Jiang B. Calcium Phosphate Cement Promotes Odontoblastic Differentiation of Dental Pulp Cells In Vitro and In Vivo. Coatings. 2022; 12(4):543. https://doi.org/10.3390/coatings12040543
5. Hilton TJ, Ferracane JL, Mancl L; Northwest Practice-based Research Collaborative in Evidence-based Dentistry (NWP). Comparison of CaOH with MTA for direct pulp capping: a PBRN randomized clinical trial. J Dent Res. 2013 Jul;92(7 Suppl):16S-22S. doi: 10.1177/0022034513484336.
6. Gonzalez-Lara A, Ruiz-Rodriguez MS, Pierdant-Perez M, Garrocho-Rangel JA, Pozos-Guillen AJ. Zinc Oxide-Eugenol Pulpotomy in Primary Teeth: A 24-Month Follow-up. J Clin Pediatr Dent. 2016;40(2):107-112. doi:10.17796/1053-4628-40.2.107
7. Soliman HA, El-Toukhy RI, Ibrahim MMA, Grawish ME, Kader Sobh MA, Mahmoud SH. Impact of corticosteroid administration on the response of exposed dental pulp to capping with bioactive cements-experimental study on mongrel dogs. BMC Oral Health. 2023 Jun 26;23(1):423. doi: 10.1186/s12903-023-03119-3.
8. McDonald and Avery Dentistry for the Child and Adolescent. Jeffrey A. Dean, David R. Avery, Ralph E. McDonald. Elsevier Health Sciences, 2011; 296–312.
9. Pribadi N, Budiarti D, Kurniawan HJ, Widjiastuti I. The NF-kB and Collagen Type 1 Expression in Dental Pulp after Treated Calcium Hydroxide Combined with Propolis. Eur J Dent. 2021 Feb;15(1):122-126. doi: 10.1055/s-0040-1716319.
10. Nakabayashi N, Watanabe A, Ikeda W. Intra-oral bonding of 4-META/MMA-TBB resin to vital human dentin. Am J Dent. 1995;8(1):37-42.
11. Swarup SJ, Rao A, Boaz K, Srikant N, Shenoy R. Pulpal response to nano hydroxyapatite, mineral trioxide aggregate and calcium hydroxide when used as a direct pulp capping agent: an in vivo study. J Clin Pediatr Dent. 2014;38(3):201-206. doi:10.17796/jcpd.38.3.83121661121g6773
12. Komabayashi T, Ebihara A, Aoki A. The use of lasers for direct pulp capping. J Oral Sci. 2015;57(4):277-286. doi:10.2334/josnusd.57.277
13. Tarim B, Hafez AA, Cox CF. Pulpal response to a resin-modified glass-ionomer material on nonexposed and exposed monkey pulps. Quintessence Int. 1998;29(8):535-542.
14. Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc. 1996;127(10):1491-1494. doi:10.14219/jada.archive.1996.0058
15. Niinuma A. Newly developed resinous direct pulp capping agent containing calcium hydroxide (MTYA1-Ca). Int Endod J. 1999;32(6):475-483. doi:10.1046/j.1365-2591.1999.00249.x
16. Nakashima M. Bone morphogenetic proteins in dentin regeneration for potential use in endodontic therapy. Cytokine Growth Factor Rev. 2005;16(3):369-376. doi:10.1016/j.cytogfr.2005.02.011
17. Goldberg M, Six N, Chaussain C, DenBesten P, Veis A, Poliard A. Dentin extracellular matrix molecules implanted into exposed pulps generate reparative dentin: a novel strategy in regenerative dentistry. J Dent Res. 2009 May;88(5):396-9. doi: 10.1177/0022034509337101.
18. Drouri S, El Merini H, Sy A, Jabri M. Evaluation of Direct and Indirect Pulp Capping With Biodentine in Vital Permanent Teeth With Deep Caries Lesions. Cureus. 2023 May 23;15(5):e39374. doi: 10.7759/cureus.39374.
19. Lee TS, Chang CC, Zhu Y, Shyy JY. Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation. 2004;110(10):1296-1302. doi:10.1161/01.CIR.0000140694.67251.9C
20. Zhu SY, Yuan CY, Lin YF, et al. Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Dental Pulp Stem Cells (DPSCs) Display a Similar Profile with Pericytes. Stem Cells Int. 2021;2021:8859902. Published 2021 Jul 24. doi:10.1155/2021/8859902
21. Rahayu RP, Pribadi N, Widjiastuti I, Nugrahani NA. Combinations of propolis and Ca(OH)2 in dental pulp capping treatment for the stimulation of reparative dentin formation in a rat model. F1000Res. 2020 Apr 29;9:308. doi: 10.12688/f1000research.22409.1.
22. Asgary S, Eghbal MJ, Parirokh M, Ghanavati F, Rahimi H. A comparative study of histologic response to different pulp capping materials and a novel endodontic cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(4):609-614. doi:10.1016/j.tripleo.2008.06.006
23. Al-Hezaimi K, Al-Tayar BA, Bajuaifer YS, Salameh Z, Al-Fouzan K, Tay FR. A hybrid approach to direct pulp capping by using emdogain with a capping material. J Endod. 2011;37(5):667-672. doi:10.1016/j.joen.2011.02.003
24. Yang IS, Lee DS, Park JT, Kim HJ, Son HH, Park JC. Tertiary dentin formation after direct pulp capping with odontogenic ameloblast-associated protein in rat teeth. J Endod. 2010;36(12):1956-1962. doi:10.1016/j.joen.2010.08.052
25. Alanezi AZ, Jiang J, Safavi KE, Spangberg LS, Zhu Q. Cytotoxicity evaluation of endosequence root repair material. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(3):e122-e125. doi:10.1016/j.tripleo.2009.11.028
26. Camargo SE, Rode Sde M, do Prado RF, Carvalho YR, Camargo CH. Subcutaneous tissue reaction to castor oil bean and calcium hydroxide in rats. J Appl Oral Sci. 2010 May-Jun;18(3):273-8. doi: 10.1590/s1678-77572010000300014. PMID: 20857007; PMCID: PMC5349050.
27. Gandolfi MG, Siboni F, Prati C. Chemical-physical properties of TheraCal, a novel light-curable MTA-like material for pulp capping. Int Endod J. 2012;45(6):571-579. doi:10.1111/j.1365-2591.2012.02013.x
28. Reddi AH. Collagen and cell differentiation. In: Biochemistry of collagen. 1976 . Ch 9 P. 449 Plenum Press, New York.
29. Patino MG, Neiders ME, Noble B, Cohen RE. Collagen as an implantable material in medicine and dentistry. J Oral Implantol. 2002;28(5): 220-5.
30. Mossa KA. The Effect of Placental Collagen Application on Extraction Wound Healing in Hamsters (Histologic study). Master thesis, College of Dentistry, Baghdad University. 2005.
31. Maršan T, Prpić-Mehičić G, Karlović I. Pulpal Response to Direct Pulp Capping with Collagen Bioresorbable Membrane. Acta Stomatol Croat. 2003;37, br. 1.
32. kakarla P, Avula1 JSS, Anche S. Collagen as a Biomaterial in Dentistry. International Journal of Innovative Medicine and Health Science. 2016; 6: 1-4.
33. Abdulrazzaq M M. A Study of the Effect of Placental Collagen on Pulp Exposure (Histological, Ultrastructural, Biochemical and Radiological In Vivo Study), Ph, D. Thesis. Abdulrazzaq M. A Study of the Effect of Placental Collagen on Pulp Exposure (Histological, Ultrastructural, Biochemical and Radiological In Vivo Study), Ph, D. Thesis. 2006. College of dentistry / Baghdad university
34. Bajić, M.P. Danilović, V. Prokić, B. Direct Pulp Capping Using Biodentine. Stomatološki glasnik Srbije. 2014;61(2):67-74.
35. Hanna, S.N. Alfayate, R.P. Prichard, J. Vital Pulp Therapy an Insight Over the Available Literature and Future Expectations. Eur Endod J. 2020; 5(1): 46–53.